This study was performed to find out the magnitude and pattern of antimicrobial uses in surgical inpatients related to overall, hospitals, diseases and surgical types. The 1,692 surgi-cal patients, treated for eleven surgical diseases (Thyroid disease, breast disease, inguinal hernia, stomach cancer, stomach ulcer, duodenal ulcer, biliary disease, small bowel disease, colorectal disease, acute appendicitis, hemorrhoid), were selected for study among the 36,018 inpatients of 10 large general hospitals, treated as medical insurance holders between January, 1982 and December, 1982.
The results of this study were. Summarized as followings.
1) The overall use of antimicrobial agents in surgical inpatients was 82.9%.
2) The uses of antimicrobial agents related to hospitals were variable from 64.4% to 100%.
3) The routes of antimicrobial agents administration were oral, injection, and both toget-her. The most common route was injection (91.7%). Single, two, and three antimicrobial agents were given to 23.9%, 43.2%, and 17.5% of patients respecitively. Even more than four antimicrobial agents were given to 15.5% of patients.
4) The most common kind of antimicrobial agent was aminoglycosides (45.2%), and next, cephalosporins (26.6%), penicillins (19.5%). According to the use of individual antimicrobial agent, the most common antimicrobial agent was gentamycin (19.3), and next, cephazolin (12.0%), ampicillin (9.1%). The most common oral antimicrobial agent was kanamycin (45.4%) used for colon preparation, and next, ampicillin (18.4%). The most common inject-able antimicrobial agent was gentamycin (20.3%), and next, cephazolin (12.6%), ampicillin (8.6%).
5) The uses of antimicrobial agents related to diseases were variable from 27.6% for ing-uinal hernia to 100% for duodenal ulcer and small bowel diseases.
6) Aminoglycosides was the most common kind of antimicrobial agent in all hospitals andfor all diseases except inguinal hernia, for that penicillins was the most commonly used.
7) The uses of antimicrobial agents for clean surgery, cieancontaminated and contaminatedsurgery, and dirty surgery were 57.9%, 94.0%, and 100% respectively.
8) The uses of antimicrobial agents for clean surgery related to hospitals were variable
from 23.7% to 100%.
9) The comparisons of average hospital days in clean surgery between antimicrobial use group and no-use group showed that average hospital days of use group were as long as or longer than that of no-use group.
10) Ampicillin was the most commonly used antimicrobial agent for clean surgery, but gen-tamycin for the others.
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